METKINEN OY


Acarbose

IUPAC Name: 5-[5-[3,4-dihydroxy-6-methyl-5-[[4,5,6-trihydroxy-3-(hydroxymethyl)

-1-cyclohex-2-enyl]amino]oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxa
n-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,4-triol

Chemical formula: C25H43NO18

Productivity: 5 G/L

Acarbose inhibits enzymes needed to digest carbohydrates: apecifically alpha-glucosidase enzymes in the brush broder of the small intestines and it inhibits pancreatic alpha-amylase. Pancreatic alpha-amylase hydrolyzes complex starches to oligosaccharides in the lumen of the small intestine, whereas the membrane-bound intestinal alpha-glucosidases hydrolyze oligosaccharides, trisaccharides, and disaccharides to glucose and other monosaccharides in the small intestine. Inhibition of these enzyme systems reduces the rate of digestion of complex carbohydrates


Products

  • Tacrolimus
  • Pravastatin
  • CoenzymeQ10
  • Acarbose
  • Lovastatin
  • Compactin


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