Strain Improvement

Natural Strain Development

Do you have ideas to start new product? Let us help you.

Process for strain development comprises of several stages.

• Data collecting on species and cultivation parameters is required for further analysis of ways to handle the strain
• Strain mutability evaluation includes period for probationary mutagenesis series when great variety of mutagen factor combinations affects the strain. All data for obtained mutants during this preliminary mutagenesis is analysed thoroughly for further stage
• Screening and selection among great deal of mutant varieties is a very demanding stage: experts' deep knowledge in combination with many years of experience and scientific intuition makes it successful
• Induced mutagenesis as the basis of Laboratory Know-How represents combination of classical methods for chemical and physical impact on the strain
• Technology parameter optimisation
• Process scale-up
• Recovery Technology Development

Strain Improvement

Not satisfied with your strain productivity or technology not optimal? Let us examine where the problem is!

Metkinen Oy has great experience in strain improvement. Laboratory experts examine thoroughly all-possible ways for strain improvement - including original technology optimization and attempts to increase strain productivity by applying unique "know-how" elaborated in Laboratory.

Process for strain improvement comprises of several stages.

• Data provided by Customer analysis: to plan further research
• Strain and Technology parameters re-production in Metkinen Oy Laboratory: required for "start point" determination
• Strain mutability evaluation includes period for probationary mutagenesis series when great variety of mutagen factor combinations affects the strain. All data for obtained mutants during this preliminary mutagenesis is considered thoroughly for further stage
• Screening and selection among great deal of mutant varieties is a very demanding stage: experts' deep knowledge in combination with many years of experience and scientific intuition makes it successful
• Induced mutagenesis as the basis of Laboratory Know-How represents combination of classical methods for chemical and physical impact on the strain
• Technology parameter optimisation
• Process scale-up
• Recovery Technology Improvement: under Customer request

Metkinen Oy issues official reports for Customer for evaluation of process progress. All research works are carried out under strict confidential terms as per Contract.